A basic vaccination series should be a part of your puppy's schedule during the first four months. A combination vaccine is given once a month from two months through four months and then once annually. It protects your puppy from leading infections and illnesses such as distemper, hepatitis, leptospirosis, parvovirus and para-influenza. If you acquired a dog that is older than four months and that has not been vaccinated, the vet will use a different protocol -- two vaccinations given two to three weeks apart and then annual vaccinations. Some breeds get vaccinated into their fifth month, including Doberman Pinschers, Rottweilers, Pit Bulls and American Staffordshire Terriers.
Your dog will also need a rabies vaccination. However, laws around the country differ about when this vaccination must be given, so check with your vet about scheduling a rabies vaccination for your dog. Your vet can also tell you about other vaccinations that may be appropriate depending on where you live.